The AllergyScreen allergen detection system adopts western blotting method, combining with the biotin avidin amplification system, which further greatly improves the sensitivity of the detection system on the basis of amplification effect of ordinary enzyme label, and uses a special detection instrument to quantitatively detect allergies in human serum Original specific IgE antibody (sIgE).
Internationally advanced and highly purified allergens are non-covalently bound to the nitrocellulose membrane, which better retains the natural conformation and the activity of the allergen, greatly improves the reliability of the system detection, and fundamentally avoids the non-specific capture method. Interference of heterosexual IgE antibody to detection.
Wide detection range
Specially aimed at the Chinese market, these products are divided into multiple combinations, only 300ul of serum for one sample can detect up to 60 most common inhaled and food allergens.
High-quality test board
Each test board is equipped with positive quality control to strictly ensure the quality of the system.
Simple and time-saving
Specially equipped with sensitive sieve detector for quantitative analysis and detection, specially equipped with incubation cassette and solid frequency mixer, simple operation, convenient, low cost, 2.5 hours to complete all experiments.
Guaranteed after-sales service, high-level professional brand service.
The allergen detection combination can better meets clinical needs
,and covering 60 most common clinical inhalation and food allergens.
Egg yolk protein
The most common dust mite allergies in China shall be tested separately for house dust mites, dust mites and tropical claw mites, especially to meet with the testing requirements of tropical claw mites for users in southern China.
Different from other products that only detect German cockroaches, items of cockroach allergens, German cockroaches, American cockroaches and oriental cockroaches are comprehensively tested for this product, which can achieve full coverage of different types of cockroaches common in different regions in China.
It can be used for silk detection and has important clinical application value in major countries with silk production and use.
It contains multiple combinations of tree and grass pollen inhalation allergens, which are used for the detection and diagnosis of spring pollen, late spring pollen, summer grass pollen and autumn pollen in different regions of southern and northern China. This series of products including quinoa / Amaranthus retroflexus test products (autumn pollen), white wax test products (spring pollen) and compound leaf maple acacia (late spring pollen) test products.
This product can be used for the detection of Aspergillus niger.
The sub-test of egg yolk and egg white are of great significance for the diagnosis of children's food allergy and the guidance of supplementary food supplement.
It can be used for buckwheat detection and escort healthy food.
The product can test with the 5 most common nut allergens, cashews, pistachios, hazelnuts, almonds and walnuts.
The authoritative global healthcare market industry report, Kalorama Information "Global In Vitro Diagnostic Report" (9th edition, 2014) pointed out: The allergen screening test strip produced and promoted by Mediwiss Analytic GmbH and approved by CE is currently the most advanced commercial diagnostic testing method.
The comparison between the target value classification of 171 CAP inter-room quality control and AllergyScreen® classification
The AllergyScreen® system has also been widely used in many national high-tech projects, such as the National "Eleventh Five-Year" Science and Technology Project (2007CB516706), the "Eleventh Five-Year" Science and Technology Support Project of the Ministry of Science and Technology (2007BAI18B15), and the key clinical disciplines of the Ministry of Health The project (07090138), a major special project of the Ministry of Agriculture (2008ZX08011-005), has been highly unanimously affirmed by experts in related fields for its authority and reliability.
The AllergyScreen system has excellent sensitivity. The results of the comparison between the AllergyScreen and the skin test are even better than the CAP system to some extent. This is mainly because the allergens in this system are not modified and not shared, just like the skin test. The valence is bound to the nitrocellulose membrane, and the system also uses a biotin-streptavidin amplification system so that even very small amounts of IgE can be detected. The AllergyScreen system is a technologically advanced and creative allergen quantitative detection system, which applies scientific research-purpose western blotting technology to daily laboratory diagnosis. The special combination of allergens for different diseases can be used for screening and testing of antibodies for many diseases. The system method is credible, quick and easy to operate, low cost, not within the reach of in vitro single allergen detection test, sensitivity and specificity are similar to skin test, and consistent with conventional in vitro single allergen detection test.
References：W. Kersten．Comparison of the AllergyScreen (MEDIWISS Analytic, Moers) with the Skin Test (HAL, Düsseldorf -in-vivo) and the CAP-System (Pharmacia, Freiburg-in-vitro)．Allergologie 2002，25 (4) : 203-208
Compared with the CAP system and skin prick test results, the AllergyScreen system has good performance and has a good application prospect. Due to the small amount of specimens required, the detection performance is good in the range of low IgE levels, which is especially suitable for children.
References：Ileana Herzum, Nicole Blümer, Werner Kersten, Harald Renz. Diagnostic and analytical performance of a screening panel for allergy. Clin Chem Lab Med. 2005，43 (9) : 963-966
As an allergen screening for newly diagnosed patients, allergen screening has credible results, moderate cost, and can be used clinically.
References：Baoqing Sun，Nili Wei，Jing Li，Nanshan Zhong . Comparative analysis of three different methods for detecting common allergens［J］．Modern hospital 2006，6（10）：52-54
The sIgE test results of the two detection systems (ImmunoCAP100 and AllergyScreenTM®) are significantly consistent with the SPT results. Taking SPT as the reference diagnostic standard, ImmunoCAP100 has high sensitivity, and AllergyScreen system has high specificity. The two detection systems have complementary effects in clinical applications. As a simple method, AllergyScreen can screen and detect many allergens. It has low cost, good consistency with SPT, and high specificity. It is suitable for screening large sample cases in clinical work. And epidemiological research.
References: Xiaodan Jiang，Guangyu Li，Jichao Shao，Xuewei Zhu，Cuida Meng，Dongdong Zhu . Study on the correlation between two kinds of serological specific IgE and skin prick test in allergic rhinitis [J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010，45(8):652-655
The difference between the two systems (ImmunoCAP and AllergyScreenTM®) is not statistically significant. AllergyScreen is a simple method that can simultaneously measure multiple allergens, with low cost and time-consuming.
References：Chengyao Liu，Demin Han，Luo Zhang，Yan Zhao . A comparative study of two serological tests in the diagnosis of allergic rhinitis [J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2009,23(11):484-487
The AllergyScreen system has higher detection sensitivity, specificity and accuracy. In view of the fact that this test is easy to operate, does not require expensive equipment, and the reagent cost is relatively low, it is expected to be widely used in clinical practice.
References：Ming Li，Zhengzheng Shen，Xia Shen . AllergyScreen system in children with type I allergy［J］．Journal of Shanghai Second Medical University 2004，24（9）：785
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